Eurolines operate direct services between Brussels and Mulhouse Brussels to Mulhouse is a distance of 252 miles (406 kilometres). Eurolines operate 1 direct buses per day. The fastest journey each day takes 7hrs 45mins. See our route guide and coach timetables below for more details. Doing a search on Coachfairer is the best way to find the fastest journeys by all operators and the cheapest prices!